Norix 1

✔️ Norix 1 is primarily used for the following conditions:

• Emergency Contraception
• Long Term Contraception

✔️ How does Norix 1 work?

Norix 1 works by managing the release and fertilization (when sperm unite with an egg) of the egg from the ovary, or by managing the attachment of a fertilized egg to the uterus (implantation

✔️ Side Effects of Norix 1

• Nausea
• Vomiting
• Lower abdominal pain
• Tiredness
• Headache
• Diarrhea
• Dizziness
• Uterine bleeding

✔️ Words of Advice:

• Levonorgestrel is a single tablet and you only have to take 1 dose to work.
• Take it as soon as possible, preferably within 12 hours and not later than 72 hours (3 days) of having unprotected sex or contraceptive failure.
• Notify your doctor if you vomit within 2-3 hours of taking this medicine.
• It is not as effective as regular methods of contraception and should be used only as an emergency measure.
• Take a pregnancy test about a week after you take Levonorgestrel as there is a 5-10% chance that it may not have worked.
• Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
• Avoid chronic stress and physical exercise like running, as it might increase vaginal bleeding.
• Monitor your blood pressure daily, and immediately contact your doctor if there is too much fluctuation.

✔️ When to Use Norix 1:

You may need Norix 1 in the following situations:

• If no contraceptive method was used during intercourse.
• If you missed three consecutive contraceptive pills.
• If your partner's condom broke, slipped, was improperly removed, or forgotten.
• If you suspect your intrauterine device (IUD) was expelled.
• If your vaginal diaphragm or contraceptive cap moved or was removed too early.
• If you fear withdrawal (pull-out method) failed or had intercourse during a high-risk period while using the rhythm method.
• In cases of sexual assault (rape).

✔️ Norix 1 – Emergency Contraceptive

Norix 1 is an emergency contraceptive for women, designed to prevent unintended pregnancy when taken within 72 hours of unprotected intercourse. It is not intended for regular contraception and is commonly referred to as the Post-Coital Pill or Morning-After Pill. The active ingredient in Norix 1 is Levonorgestrel.

✔️ Understanding the Menstrual Cycle & Contraception

• The menstrual cycle is the time between two menstrual periods, typically lasting 28 days but varying among women.
• Ovulation occurs around the middle of the cycle when an ovary releases an egg. However, it can happen at any time.
• If sperm meets the egg, fertilization can occur, leading to pregnancy if the fertilized egg implants in the uterus.

✔️ Types of Contraception:

• Prevents ovulation (e.g., birth control pills)
• Blocks fertilization (e.g., condoms)
• Stops implantation (e.g., intrauterine devices - IUDs)

✔️ Important Considerations:

• Emergency contraception like Norix 1 works by delaying ovulation or preventing implantation if taken in time. However, if implantation has already occurred, it will not be effective.
• If you do not use regular contraception, consult a doctor for advice on a suitable birth control method.
• If you have unprotected sex, you may also be at risk of sexually transmitted infections (STIs) or HIV. If unsure of your partner's health status, consult a doctor for early testing and treatment.
• For future protection, use effective contraception and practice safe sex to prevent pregnancy and infections.

✔️ Pharmacology of Norix 1 (Levonorgestrel):

• Levonorgestrel suppresses hormone signals that trigger ovulation by binding to progesterone and androgen receptors.
• It slows the release of gonadotropin-releasing hormone (GnRH), preventing the luteinizing hormone (LH) surge that causes ovulation.
• This prevents egg release from the ovary, making it most effective when taken before ovulation.

✔️ Dosage Guidelines for Norix 1 (Levonorgestrel)

1. Emergency Contraception (Post-Coital Pill)

• Single Dose Option: 1.5 mg as soon as possible, preferably within 12 hours, but no later than 72 hours after unprotected intercourse.
• Two-Dose Option: 750 mcg as soon as possible within 72 hours, followed by a second dose 12 hours later.
• Effectiveness: The sooner it is taken, the more effective it will be in preventing pregnancy.

2. Menopausal Hormone Replacement Therapy (HRT)

• Used as the progestogenic component in hormone therapy.
• Dosage: 75-250 mcg daily for 10-12 days of a 28-day cycle.

3. Contraception (Daily Birth Control)

• Monotherapy (Progestin-Only Pill): 30-37.5 mcg daily for continuous use.

✔️ Directions for Use: Norix 1

Take Norix 1 as advised by your physician. Take Norix 1 within 72 hours after unprotected sexual intercourse. Swallow the medicine with water and do not crush or chew the medicine.

✔️ Overdose & Management

If too much OPTION 72 Tablet is accidentally taken, seek immediate medical attention or visit a hospital.

Symptoms of Overdose: Nausea, Vomiting, Vaginal bleeding

If an overdose occurs, a healthcare provider should be consulted immediately for appropriate management.

✔️ Drug Interactions

Before taking Norix 1 Tablet, inform your doctor if you are using any of the following medications, as they may affect its effectiveness:

Epilepsy Medications

• Barbiturates (e.g., phenobarbital)
• Phenytoin, primidone, carbamazepine, oxcarbazepine, topiramate, felbamate

Tuberculosis Medications

• Rifampicin, rifabutin

HIV Medications

• Ritonavir, efavirenz

Fungal Infection Medications

• Griseofulvin

Herbal Remedies

• St John’s Wort (used for depression)

Immunosuppressants

• Cyclosporin

Other Hormonal Medications

• Ulipristal acetate (used for uterine fibroids)

Pulmonary Hypertension Medications

• Bosentan

✔️ Contraindications:

If you have hypersensitivity to levonorgestrel or any of the excipients of Levonorgestrel.

✔️ Who Should Avoid Taking Norix 1?

Do not take Norix 1 Emergency Contraceptive Tablet if you:

• Are allergic to Norix 1 or any of its ingredients
• Have a heart condition (e.g., artificial valve, high blood pressure, high cholesterol)
• Suffer from asthma
• Have a blood clot disorder or bleeding disorder
• Have liver or kidney disease
• Have anemia (low hemoglobin levels)
• Have salpingitis (inflammation of the fallopian tubes)
• Are malnourished

Taking Norix 1 under these conditions can lead to serious health complications.

✔️ Precautions:

• Norix 1l does not terminate an existing pregnancy. It only prevents pregnancy if taken within 72 hours of unprotected intercourse.
• Avoid driving or operating heavy machinery after taking Norix 1.
• St. John’s Wort (a herbal remedy for depression) should be avoided as it may reduce the effectiveness of Norix 1.
• If you are breastfeeding, consult your doctor before taking Norix 1 to assess potential risks.
• Norix 1 is not recommended for individuals under 16 years old.
• Norix 1 should not replace regular contraceptive methods.

✔️ Storage:

• Do not use the tablet beyond the expiry date mentioned on the packaging.
• Keep the tablet in its original outer carton to protect it from moisture and light.
• Store the medicine in a safe place, away from children.
• Store in a cool, dry place below 30°C to maintain its effectiveness.